Bioinformatics operators

5 operators in the bioinformatics category of the live registry. Compose them in a contract or call POST /api/zeq/compute — KO42 is always on, plus up to three more per call.

How it computes: dedicated closed-form solver solveStructural — real equations over CODATA-2018 constants; where an operator needs a series/matrix/field a scalar cannot express, it refuses honestly. See the solvers.

Operator	Description	Equation
`BIO_BLAST_EVALUE`	BLAST E-value estimating the expected number of alignments with score at least S occurring by chance in a database search.	`E = K \cdot m \cdot n \cdot e^{-\lambda S}`
`BIO_GC_CONTENT`	GC content ratio measuring the proportion of guanine and cytosine bases in a DNA or RNA sequence.	`\text{GC} = \frac{n_G + n_C}{n_A + n_T + n_G + n_C} \times 100\%`
`BIO_HIDDEN_MARKOV`	Hidden Markov Model forward probability for gene prediction and sequence annotation in computational genomics.	`\alpha_t(j) = \sum_{i=1}^{N} \alpha_{t-1}(i) \cdot a_{ij} \cdot b_j(o_t)`
`BIO_PHYLO_DIST`	Jukes-Cantor evolutionary distance model estimating the number of nucleotide substitutions per site between two DNA sequences.	`d = -\frac{3}{4} \ln\left(1 - \frac{4}{3}p\right)`
`BIO_SEQ_ALIGN`	Smith-Waterman local sequence alignment score for finding optimal local alignments between two biological sequences.	`H(i,j) = \max\{0, H(i-1,j-1)+s(a_i,b_j), H(i-1,j)-d, H(i,j-1)-d\}`

Compute one — a real call

Ask the operator which inputs it needs (the honesty contract refuses empty inputs rather than inventing them):

curl -sS -X POST https://zeqsdk.com/api/zeq/operator-spec \
  -H "Content-Type: application/json" \
  -d '{"operator":"BIO_BLAST_EVALUE"}'

Compute one — a real call​

See also​

Compute one — a real call

See also